Ingrid Leguerney

, par  Ingrid Leguerney

Ingénieur de recherche Imagerie

Activités et thématiques de recherche

Imagerie in vivo
Imagerie ultrasonore moléculaire
Évaluation de molécules thérapeutiques en oncologie
Rédaction/Réalisation des protocoles d’imagerie et des projets éthiques
Formation à l’imagerie ultrasonore du petit animal

Contact : Ingrid.Leguerney

Gustave Roussy - Plateforme ultrasonore préclinique
114 rue Edouard Vaillant
94805 Villejuif

Tél : 01 42 11 48 26

Publications

► Molecular Ultrasound Imaging Using Contrast Agents Targeting Endoglin, Vascular Endothelial Growth Factor Receptor 2 and Integrin.
Leguerney I, Scoazec JY, Gadot N, Robin N, Pénault-Llorca F, Victorin S, Lassau N.
Ultrasound Med Biol. 2015 Jan ;41(1):197-207.Epub 2014 Oct 11.

► Dynamic Contrast-Enhanced Ultrasound Parametric Maps to Evaluate Intratumoral Vascularization.
Pitre-Champagnat S, Leguerney I, Bosq J, Peronneau P, Kiessling F, Calmels L, Coulot J, Lassau N.
Invest Radiol. 2015 Apr ;50(4):212-7

► Numerical modelling of the flow of the ultrasound contrast agents in tumour microvasculature.
Boyer L, Le Notre P, Thomas SR, Leguerney I, Lassau N, Pitre-Champagnat S.
Comput Methods Biomech Biomed Engin. 2014 ;17 Suppl 1:18-9.

► Establishment and characterization of new orthotopic and metastatic neuroblastoma models.
Daudigeos-Dubus E, LE Dret L, Rouffiac V, Bawa O, Leguerney I, Opolon P, Vassal G, Geoerger B.
In Vivo. 2014 Jul-Aug ;28(4):425-34.

► Impact of the arterial input function on microvascularization parameter measurements using dynamic contrast-enhanced ultrasonography.
Gauthier M, Pitre-Champagnat S, Tabarout F, Leguerney I, Polrot M, Lassau N.
World J Radiol. 2012 Jul 28 ;4(7):291-301.

► Assessment of quantitative perfusion parameters by dynamic contrast-enhanced sonography using a deconvolution method : an in vitro and in vivo study.
Gauthier M, Tabarout F, Leguerney I, Polrot M, Pitre S, Peronneau P, Lassau N.
J Ultrasound Med. 2012 Apr ;31(4):595-608.

► Combining functional imaging and interstitial pressure measurements to evaluate two anti-angiogenic treatments.
Leguerney I, Lassau N, Koscielny S, Rodrigues M, Massard C, Rouffiac V, Benatsou B, Thalmensi J, Bawa O, Opolon P, Peronneau P, Roche A.
Invest New Drugs. 2012 Feb ;30(1):144-56. Epub 2010 Oct 6.

► Estimation of intra-operator variability in perfusion parameter measurements using DCE-US.
Gauthier M, Leguerney I, Thalmensi J, Chebil M, Parisot S, Peronneau P, Roche A, Lassau N.
World J Radiol. 2011 Mar 28 ;3(3):70-81.

► Contrast ultrasonography : necessity of linear data processing for the quantification of tumor vascularization.
Peronneau P, Lassau N, Leguerney I, Roche A, Cosgrove D.
Ultraschall Med. 2010 Aug ;31(4):370-8. Epub 2010 Jun 24.

► Spatial distribution of anisotropic acoustic impedance assessed by time-resolved 50-MHz scanning acoustic microscopy and its relation to porosity in human cortical bone.
Saïed A, Raum K, Leguerney I, Laugier P.
Bone. 2008 Jul ;43(1):187-94. Epub 2008 Mar 7.

► Variations of microstructure, mineral density and tissue elasticity in B6/C3H mice.
Raum K, Hofmann T, Leguerney I, Saïed A, Peyrin F, Vico L, Laugier P.
Bone. 2007 Dec ;41(6):1017-24. Epub 2007 Sep 7.

► Ultrasonic backscatter and attenuation (11-27 MHz) variation with collagen fiber distribution in ex vivo human dermis.
Bridal SL, Fournier C, Coron A, Leguerney I, Laugier P.
Ultrason Imaging 2006 Jan ;28(1):23-40.

► Assessment of bone structure and acoustic impedance in C3H and BL6 mice using high resolution scanning acoustic microscopy.
Hofmann T, Raum K, Leguerney I, Saïed A, Peyrin F, Vico L, Laugier P.
Ultrasonics 2006 Dec 22 ;44 Suppl 1:e1307-11. Epub 2006 Jun 5.

► Site-matched assessment of structural and tissue properties of cortical bone using scanning acoustic microscopy and synchrotron radiation muCT.
Raum K, Leguerney I, Chandelier F, Talmant M, Saïed A, Peyrin F, Laugier P.
Phys Med Biol. 2006 Feb 7 ;51(3):733-46. Epub 2006 Jan 19.

► Bone microstructure and elastic tissue properties are reflected in QUS axial transmission measurements.
Raum K, Leguerney I, Chandelier F, Bossy E, Talmant M, Saïed A, Peyrin F, Laugier P.
Ultrasound Med Biol. 2005 Sep ;31(9):1225-35.

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